All that these different gas blends are is really a balance beam for different risks. You need the training to decide what risk that you consider acceptable and learn how to best manage those risks by smart and competent diving.
I know that Perrone has been asking quite a few of the questions on this thread, but reading it is proving to be very educational for me ... Quite a few things I didn't realize about Helium... I'm not really into deep dives so hadn't really explored tri-mixes ... I've been to about 165 (on air)... but I start to feel a little narcosis at about 150 so I'm not real comfortable going much deeper than that .. I've got lots of buddies that have been over 200 on air though (seems that I recall that about 230' is where oxygen toxicity becomes a real danger on air - anybody more versed in deep and tech diving may want to elaborate or correct me on that).
I dive nitrox whenever possible (and I use 1.6 to establish my m.o.d. - I figure that with 2 partial pressures being the point where oxygen toxicity becomes a real risk, that it still leaves a comfortable safety margin)... I don't usually need to go much deeper than 110... If there is a wreck or something I want to see that is down at 130-150 or so then I use air....
The other thing I do when diving is take extra care to keep myself hydrated... I drink tons of gatorade (should drink more water than I do - and that I will remedy), and very limited alcohol (maybe a little more after the last day of diving) .. I've read that dehydration can be a big contributing factor to DCS.
I think it has been said by many on this forum in one way or another that each person has to dive within their own comfort level and in a manner they consider safe....
Thanks for the wealth of shared information. I'm looking forward to meeting and diving with folks on future trips.